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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNH6
All Species:
29.39
Human Site:
S451
Identified Species:
71.85
UniProt:
Q9H252
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H252
NP_110406.1
994
109925
S451
L
G
K
R
Y
N
G
S
D
P
A
S
G
P
S
Chimpanzee
Pan troglodytes
XP_525954
1196
134979
S602
I
G
K
R
Y
N
D
S
D
S
S
S
G
P
S
Rhesus Macaque
Macaca mulatta
XP_001116131
994
109992
S451
L
G
K
R
Y
N
G
S
D
P
A
S
G
P
S
Dog
Lupus familis
XP_853319
957
106637
S451
L
G
K
R
Y
N
G
S
D
P
A
S
G
P
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9ER47
1195
135008
S602
I
G
K
R
Y
N
D
S
D
S
S
S
G
P
S
Rat
Rattus norvegicus
O54853
950
105687
S451
L
G
K
Q
Y
N
G
S
D
P
A
S
G
P
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511873
1200
135504
S602
I
G
K
R
Y
N
Q
S
D
A
S
S
G
P
S
Chicken
Gallus gallus
Q9PT84
526
59775
P33
Y
R
T
I
S
Q
I
P
Q
F
T
L
N
F
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_688778
1181
131984
S611
I
G
K
Q
Y
N
I
S
D
D
A
S
G
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q02280
1174
126352
P428
I
W
S
N
D
T
G
P
E
L
V
N
G
P
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.2
97.5
86.8
N.A.
52.8
86.2
N.A.
52.6
47.3
N.A.
51.5
N.A.
33.6
N.A.
N.A.
N.A.
Protein Similarity:
100
64.1
98.7
88.8
N.A.
63.2
88.5
N.A.
63.6
50.5
N.A.
61.4
N.A.
49.8
N.A.
N.A.
N.A.
P-Site Identity:
100
73.3
100
100
N.A.
73.3
93.3
N.A.
73.3
0
N.A.
73.3
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
86.6
100
100
N.A.
86.6
100
N.A.
86.6
0
N.A.
86.6
N.A.
46.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
10
50
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
20
0
80
10
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% F
% Gly:
0
80
0
0
0
0
50
0
0
0
0
0
90
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
50
0
0
10
0
0
20
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
80
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
40
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
80
0
0
0
0
0
10
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
20
0
40
0
0
0
90
0
% P
% Gln:
0
0
0
20
0
10
10
0
10
0
0
0
0
0
0
% Q
% Arg:
0
10
0
60
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
10
0
10
0
0
80
0
20
30
80
0
0
90
% S
% Thr:
0
0
10
0
0
10
0
0
0
0
10
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
80
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _